基本情况
成金花，女，中共党员。现任五邑大学药学与食品工程学院专任教师。主要研究益生菌在抗菌、调节肠道菌群，改善代谢性疾病等方面的机制。益生菌的产业化开发。
联系方式
地址：广东省江门市蓬江区迎宾大道中99号，五邑大学药学与食品工程学院
邮编：529020
邮箱：jhcheng@wyu.edu.cn
工作经历
2020年3月至2024年12月，韩国明知大学生效评估中心，研究教授
2015年3月至2020年 2月，韩国明知大学生命科学系，助理教授
2011年9月至2015年2月，韩国农生命食品医药素材开发中心，博士后研究员
教育及学习经历
2004年9月 - 2011年 8月，韩国明知大学，博士
2002年9月 - 2004年 8月，韩国明知大学，硕士
1998年9月 - 2002年6月，中央民族大学，生物化学系，学士
主要研究方向
(1)益生菌的搜集，鉴定，安全性评估，益生菌产品开发
从发酵食品，环境，动物，人体搜集益生菌，培养发酵，安全性评估。
(2)乳酸菌和肠道微生态与疾病的相关性研究
利用益生菌调节菌群稳态防治疾病，如高尿酸症，脂肪肝，牙周炎，帕金森症等。
(3)微生物发酵
微生物发酵提高生物活性，开发具有抗氧化、美白、抗皱等功能性化妆品。
微生物发酵液提取新型抗菌活性物质。
近三年发表学术论文
1. Cheng, J.#, Cho, J.-H#., Suh, J.-W. Characterization of Human Breast Milk-Derived Limosilactobacillus reuteri MBHC 10138 with Respect to Purine Degradation, Anti-Biofilm, and Anti-Lipid Accumulation Activities. Antibiotics. 2024; 13: 964.
2. Gu, M., Nguyen, H. T., Cho, J. H., Suh, J. W., & Cheng, J*. Characterization of Leuconostoc mesenteroides MJM60376 as an oral probiotic and its antibiofilm activity. Molecular oral microbiology. 2023;38(2):145-157.
3. Gu M, Werlinger P, Cho J-H, Jang N, Choi SS, Suh J-W, Cheng J*. Lactobacillus pentosus MJM60383 Inhibits Lipid Accumulation in Caenorhabditis elegans Induced by Enterobacter cloacae and Glucose. International Journal of Molecular Sciences. 2023; 24(1):280.
4. Gu M, Cho JH, Suh JW, Cheng J*. Potential oral probiotic Lactobacillus pentosus MJM60383 inhibits Streptococcus mutans biofilm formation by inhibiting sucrose decomposition. J Oral Microbiol. 2023;15(1):2161179.
5. Lee, HY., Lee, GH., Kim, JH. et al. Ixeris dentata and Lactobacillus gasseri media protect against periodontitis through Nrf2-HO-1 signalling pathway. Sci Rep 2023; 13, 12861.
6. Nguyen HT, Gu M, Werlinger P, Cho JH, Cheng J*, Suh JW. (2022) Lactobacillus sakei MJM60958 as a Potential Probiotic Alleviated Non-Alcoholic Fatty Liver Disease in Mice Fed a High-Fat Diet by Modulating Lipid Metabolism, Inflammation, and Gut Microbiota. Int J Mol Sci. 2022 Nov 3;23(21):13436.
7. Werlinger P, Nguyen HT, Gu M, Cho JH, Cheng J*, Suh JW. (2022) Lactobacillus reuteri MJM60668 Prevent Progression of Non-Alcoholic Fatty Liver Disease through Anti-Adipogenesis and Anti-inflammatory Pathway. Microorganisms. 2022 Nov 7;10(11):2203.
8. Zhou, B., Shetye, G., Wolf, N. M., Chen, S. N., Qader, M., Ray, G. J., Lankin, D. C., Cho, S., Cheng, J., Suh, J. W., Franzblau, S. G., McAlpine, J. B., & Pauli, G. F. (2022). New Rufomycins from Streptomyces atratus MJM3502 Expand Anti-Mycobacterium tuberculosis Structure-Activity Relationships. Organic letters, 24(40), 7265–7270.
9. Nguyen, H. T., Choi, Y. H., Choi, C. W., Suh, J. W., & Cheng, J*. (2022). Enhanced anti-wrinkle activity of adlay bran fermented with Lactobacillus brevis MJM60390. Journal of cosmetic dermatology, 21(11), 6351–6362.
10. Nguyen, Huong T., Mingkun Gu, Chun Whan Choi, Yun-Hyeok Choi, Joo-Won Suh, and Jinhua Cheng* (2022) Enhanced Anti-Melanogenic Effect of Adlay Bran Fermented with Lactobacillus brevis MJM60390. Applied Microbiology 2: 502-515.
11. Mingkun Gu#, Jinhua Cheng#, Yeong-Gun Lee, Joo-Hyung Cho, Joo-Won Suh (2022) Discovery of Novel Iminosugar Compounds Produced by Lactobacillus paragasseri MJM60645 and Their Anti-Biofilm Activity against Streptococcus mutans. Microbiol Spectr. 2022;10(4):e0112222.
12. Youjin Lee, Pia Werlinger, Joo-Won Suh, Jinhua Cheng* (2022) Potential Probiotic Lacticaseibacillus paracasei MJM60396 Prevents Hyperuricemia in a Multiple Way by Absorbing Purine, Suppressing Xanthine Oxidase and Regulating Urate Excretion in Mice. Microorganisms. 10, 851.
13. Youjin Lee, Neagawooridwimeu Kim, Pia Werlinger, Dong-A Suh, Hanki Lee, Joo-Hyung Cho, Jinhua Cheng* (2022) Probiotic Characterization of Lactobacillus brevis MJM60390 and In Vivo Assessment of Its Antihyperuricemic Activity. J Med Food 25 (4) 2022, 367–380.
申请及授权专利
(1) Joo-Won Suh; Jinhua Cheng; Joo-Hyung Cho ; Novel Lactobacillus sakei strain capable of improving fatty liver and use thereof, 2023-9-11, 韩国, 10-2022-0156590 (授权专利)
(2) Joo-Won Suh; Jinhua Cheng; Joo-Hyung Cho ; Novel Lactobacillus reuteri strain capable of improving fatty liver and use thereof, 2023-9-11, 韩国, 10-2022-0156589 (授权专利)
(3) Joo-Won Suh; Jinhua Cheng; Joo-Hyung Cho ; Novel Streptococcus salivarius strain with serum uric acid level reducing effect and renal protective effect, and use of the same, 2023-10-31, 韩国, 10-2022-0173602 (授权专利)
(4) Joo-Won Suh; Jinhua Cheng ; Novel compound with anti-biofilm formation activity and use of the same, 2024-2-14, 韩国, 10-2022-0012335 (授权专利)
(5) Joo-Won Suh; Jinhua Cheng ; Novel strain with serum uric acid level reducing effect and renal protective effect, and use of the same, 2024-11-26, 韩国, 10-2021-0160118 (授权专利)
(6) Jinhua Cheng; Joo-Won Suh; Min-Ji Cho ; Novel Mesorhizobium soli strain capable of degrading organochlorine pesticide and use of the same, 2022-5-16, 韩国, 10-2020-0136171 (授权专利)
(7) Jinhua Cheng; JOO-WON SUH; Min-Ji Cho; Kyu-Jin Yeom; Chan-Ho ; Novel Streptomyces sp. capable of degrading organochlorine pesticide in soil and use of the same, 2021-4-5, 韩国, 10-2019-0140482 (授权专利)
(8) Jinhua Cheng; JOO-WON SUH ; Novel Streptomyces sp. capable of degrading organochlorine pesticide and use of the same, 2021-2-17, 韩国, 10-2018-0152276 (授权专利)
(9) Jinhua Cheng; JOO-WON SUH ; A composition comprising extract of Artemisia and Engineering EGF for anti-wrinkle or moisturizing , 2021-11-12, 韩国, 10-2019-0140040（授权专利）
